Born to theatrical parents, Katherine Mallen Kupferer made her professional stage debut in Chicago Shakespeare Theater's acclaimed production of Gypsy and her major motion picture debut in Steve McQueen's Widows. Most recently, she can be seen as Gretchen in Lionsgate's long-anticipated film adaptation of Judy Blume's beloved classic Are You There God, It's Me, Margaret. (오뜨랑에서 실시간으로 번역된 한글 프로필도 확인할 수 있어요) 2026년 마우스에서 Minnie Dunn 역을 맡았다. 2025년 They Rescue Horses, Don’t They?에서 Aubrey 역을 맡았다. 2024년 고스트라이트에서 Daisy 역을 맡았다.