Franklin was born to father Howard Franklin, a screenwriter and director. His stepmother is DJ Anne Litt. Franklin attended high school at Campbell Hall School in Studio City, California. He graduated from New York University Tisch School of the Arts.
Franklin's first major role was a recurring role as Nick, the I.T. worker on NBC's The Office. Franklin later went on to appear as a series regular on the short-lived FOX comedy series Traffic Light. He appears with another Office actor, David Denman, who played Pam's ex-fiancée Roy. His side projects include a short for Funny or Die: a fake commercial promoting the Dudes-N-Bros Talking Points System, which is a service that helps guys who aren't dudes or bros hold a conversation with dudes and bros. He co-starred on the CBS sitcom The Millers and appeared on FOX sitcom New Girl, the HBO political comedy Veep, Black-ish, and Abby's. 넬슨 프랭클린(1985년생) 는 배우로, 대표작으로 어느 허무명랑한 인생, Answer This!, 베이직이 있으며, 그 외에도 오피스, 에이전트 오브 쉴드, 뉴 걸, 고스트, 못 말리는 패밀리, 나의 직장상사는 코미디언, 블랙키시, 옐로우재킷, 그로운-이시, 부통령이 필요해, 어 밀리언 리틀 씽즈, 인형의 집 등 다양한 작품에 출연했다. 특히 2026년에는 소셜 레코닝에도 참여해서 활동중이다. (오뜨랑에서 실시간으로 번역된 한글 프로필도 확인할 수 있어요) 2026년 Wake에 출연했다. 2026년 Eternally Yours에서 Glen 역을 맡았다. 2026년 소셜 레코닝에서 Tom 역을 맡았다.